Adults with chronic kidney disease or high-risk kidney phenotypes
DESIGN TARGETAdvancing clinical research and health outcomes
Research built where it matters.
Nexus Health Research Alliance builds African-led, globally connected research platforms that turn representative data into better clinical decisions, stronger health systems and more equitable discovery.
COHCohortsConnected by Nexus
COH
Representative participants and longitudinal outcomes anchor every discovery.
01Representative cohorts
Built around local populations, priorities and care pathways.
02Integrated discovery
Connecting clinical, biological, environmental and digital evidence.
03Translational value
Moving knowledge towards practice, policy and future trials.
FLAGSHIP STUDY
Understanding why kidney disease progresses differently.
NexusGen CKD Ghana is a planned longitudinal platform for adults with chronic kidney disease or high-risk kidney phenotypes. It brings together clinical phenotyping, biospecimens, biomarkers, imaging, genomics, environmental exposures and digital measures to identify drivers of progression and cardio-renal risk.
Participants with richer biological, imaging and mechanistic assessment
NESTED COHORTKidney, cardiovascular and mortality outcomes over time
LONGITUDINAL DESIGNBetter prediction and a future trial-ready research resource
TRANSLATIONAL GOALRESEARCH IN CONTEXT
Science shaped around real clinical questions.
Nexus connects clinical care, laboratory science, data and technology so that discovery begins with the health priorities it is intended to serve.
01 · OUR PURPOSE
Evidence should represent the people it is meant to serve.
Major gaps in clinical data, genomics and longitudinal research continue to limit how well health evidence reflects diverse populations.
Nexus brings together clinicians, scientists, institutions and technology partners to create durable research platforms with local leadership and global relevance.
How we work02 · THE NEXUS MODEL
From local questions to globally useful evidence.
We build the scientific, operational and partnership architecture required for discovery that lasts beyond a single study.
ACTIVE STAGE · 01
What is happening, and to whom?
01Representative cohorts
02Clinical pathways
03Longitudinal outcomes
OUTPUT
A trusted picture of disease burden, variation and unmet need.
03 · RESEARCH PROGRAMMES
Platforms for consequential health questions.
Our programmes combine disease-specific scientific depth with shared infrastructure for data, biospecimens, governance and collaboration.
01
FLAGSHIP DISCOVERY PLATFORM
NexusGen CKD Ghana
A longitudinal platform integrating clinical phenotyping, genomics, biomarkers, vascular and retinal imaging, environmental exposures and AI-enabled modelling.
02
CARDIOMETABOLIC RESEARCH
Diabetes and cardiovascular outcomes
Clinical and population research examining the mechanisms and outcomes connecting metabolic disease with cardiovascular risk.
03
MULTICENTRE OUTCOMES
Valvular disease and arrhythmia
Collaborative research designed to improve understanding of structural heart disease and rhythm disorders across diverse care settings.
Flagship platform
NexusGen CKD Ghana
A Ghana-led longitudinal discovery platform created to explain why chronic kidney disease progresses differently from one person to another, and to translate those insights into better risk prediction and future intervention research.
Explore NexusGen CKDAdults with CKD or high-risk kidney phenotypes
Participants with richer mechanistic assessment
Kidney, cardiovascular and mortality outcomes
Clinical, genomic, biological, imaging, exposure and digital data
04 · RESEARCH INFRASTRUCTURE
Designed to support discovery responsibly.
Nexus coordinates the systems that turn individual studies into a durable, trusted research resource.
Research data architecture
Standardised, analysis-ready clinical and scientific datasets designed for longitudinal use.
Biospecimen science
Quality-controlled collection, cold chain, storage and biomarker-ready sample governance.
Ethics and governance
Informed consent, Ghanaian institutional oversight and controlled scientific access.
Capacity development
Infrastructure, mentorship and research leadership embedded within participating institutions.
WORK WITH NEXUS
Choose the conversation that fits your contribution.
Each pathway takes you to a focused enquiry form without exposing private contact details.
01 · CLINICAL
Sites and investigators
Clinical populations, specialist expertise, recruitment pathways and longitudinal follow-up.
02 · SCIENTIFICResearchers and laboratories
Biomarkers, genomics, imaging, epidemiology, data science and methodology.
03 · TECHNOLOGYPlatform providers
Validated technologies for phenotyping, data capture, monitoring and research operations.
04 · FUNDINGFunders and translational partners
Support for representative discovery, capacity development and responsible scale-up.
05 · COLLABORATIVE BY DESIGN
Institutional, scientific and technology partners.
Partnerships contribute clinical access, scientific expertise, laboratory capacity, technology and infrastructure while research direction and interpretation remain independent.
01Korle Bu Teaching Hospital
02University of Ghana Medical Centre
03Noguchi Memorial Institute for Medical Research
04University of Ghana
05Nordic Bioscience
06Activinsights
07B Medical Systems
BUILD WITH US
Better research begins with the right nexus.
We welcome partnerships aligned with representative science, local leadership, participant protection and long-term research value.
Start a conversation